Alzheimer’s Disease (AD) is a serious degenerative brain disease that affected an estimated 5.4 million Americans in 2016— a number that is estimated to only increase as the aging population continues to grow. Early diagnosis is critical in working to control disease progression, and new research has suggested this may soon be easier than ever before. A team of international researchers have recently published their research on developing a blood test for diagnosing Alzheimer’s using biomarkers for the disease found in the blood.
In their research, the team have developed technology that detects brain tau protein, a hallmark of AD, in the blood platelets of patients. Then they use the the ratio between this anomalous tau and the normal tau protein to help distinguish AD patients from normal controls. They believe this finding is a step forward in using of biomarkers, not only for clinical purposes, but also for research dedicated to better understand the pathology of AD.
This is not the first time researchers have tried to develop a blood test for an Alzheimer’s diagnosis. Earlier this year, a study published in Journal of Alzheimer’s Disease focused on using levels of a protein called clusterin, alongside other factors in a computer model, to help accurately determine which dementia patients would go on to develop AD.
What’s more, a study published in 2015 delved to make AD diagnosis by attempting to find the disease using patient’s saliva. For the study, researchers at the University of Alberta, Edmonton found specific metabolites , which are the molecular byproducts of metabolism, present in saliva could indicate metabolic changes in the brain signifying early stages of Alzheimer’s. They then used linked the presence of certain metabolites in saliva with a person’s cognitive abilities. For example, the presence of certain metabolites was associated with higher levels of cognitive decline. Although still in the early stages of research, a saliva test for AD would provide an easy and affordable way to get this test to more people who need it.
Guys I gotta tell you. This is one of the only illnesses that scares me to death. This is so not fair. I remember a relative of mine had either Dementia or AD. I wasn’t around much, but from what I heard, it’s not good. She would drive to a location and forget why. She’d forget how to get back home. Imagine having a loved one go through this.
I was doing research the other night because every now and then I have an interest in learning something. Well I never understood how AD OR Dementia killed anyone. I didn’t know it was about a deterioration of the brain or nerve damage. I honestly thought it was just about forgetting how to do things. I figured people were dying because they weren’t eating, forgot how to take vital life saving medications.
Dementia = a chronic or persistent disorder of the mental processes caused by brain disease or injury and marked by memory disorders, personality changes, and impaired reasoning.
Alzheimer’s Disease= Alzheimer’s disease is an irreversible, progressive brain disorder that slowly destroys memory and thinking skills, and eventually the ability to carry out the simplest tasks. In most people with Alzheimer’s, symptoms first appear in their mid-60s. Estimates vary, but experts suggest that more than 5 million Americans may have Alzheimer’s.
And from my understanding it’s not like HBP or Diabetes that can stem from genetics. Even if nobody in your family had it, you could still be diagnosed with it.
I’ve been the one person who had such a fucked up childhood that I’ve literally begged the universe to help me forget. I don’t want to remember certain things or people. But I don’t want this. I’m starting to realize that maybe the essence of who I am is tied in to my past experiences. I hate to think that way though.
My heart goes out to anyone who is suffering from this horrible life stealing condition and the family members who are there to try and help them. This is definitely a cause worth giving to.
A friend of mine was telling me about his grandfather. He said he was a grown man looking at his grandfather, but his grandfather kept asking for him and kept seeing him as a little boy. Then his grandfather called a family member to help him out because according to him, some fat woman wouldn’t let him leave the house. That woman was actually his daughter. He didn’t remember her. And she was trying to prevent him from leaving because he continued to get lost.